Linda Peckel

Headaches are a common occurrence in the general population and are often present in patients with an underlying brain tumor, although it is not yet clear to what degree they are related.

Acute confusional migraine has not been specifically studied and many clinicians remain unaware of the condition, which may result in underestimation of the prevalence.

A revised focus on exercise training for MS is advocated by a number of recent reviews, all showing benefits to cardiovascular and muscular fitness and improved quality of life in MS.

Nonpharmacological strategies, including bed rest, have a lack of evidence supporting their use in the treatment of postdural puncture headache.

Neurology Advisor spoke with Dr Peter McAllister about how to best discern migraine with aura from stroke.

It is important for clinicians to quickly and accurately determine potential underlying causes and to prescribe treatments that take into account comorbidities and medications that older patients may be taking for them.

Clinicians discuss the clinical implications of headache and comorbid sleep disturbances.

Although the main risks associated with migraine include ischemic and hemorrhagic stroke, new evidence suggests that the risks for venous thromboembolism and atrial fibrillation — but not heart failure or peripheral artery disease — are also higher.

Research on therapies that may rouse a patient in a persistent vegetative state needs to include the ethical considerations of waking a patient in a state of incomplete recovery.

Headache screening should be a routine part of a prenatal visit so that if and when a patient presents with an attack, a suitable plan of action is already established.

Because of dementia’s prolonged disease course, advance care decisions and planning are often overlooked until it is too late.

While there is some moderate quality evidence supporting the use of onabotulinumtoxinA for the treatment of tension-type headache, it is not adequate enough to influence current clinical practice.

Increasing evidence suggests a relationship between migraine and MS that is beyond basic comorbidity.

The judicious use of caffeine as adjuvant therapy to over-the-counter pain relievers can improve or relieve pain for patients with migraine or tension-type headaches.

Several studies have uncovered sex-dependent variations in the symptomatic manifestations of Parkinson disease, as well as in the response to dopamine therapies.

The 2017 revision takes aim at better differentiating relapsing-remitting and primary-progressive forms of multiple sclerosis.

The responsibility for discussing cessation of driving in patients with mild cognitive impairment or dementia often rests on the clinician, who may have little preparation for this difficult conversation.

Numerous factors are likely contribute to the rate of progression, with different combinations of factors showing relevance for individual patients.

Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Despite mounting evidence suggesting the contrary, the debate on the potential benefits of patent foramen ovale closure for migraine is still ongoing.

Risk for mortality in posttraumatic epilepsy is high, and negative outcomes affecting cognitive, affective, and physical function are common.

While parkinsonian disorders share a common mechanism of protein aggregation, manifestations are quite varied.

The 2 treatments for cluster headache with Level A recommendations are either not readily accessible via public or private insurance or are not recommended in a large subset of patients with cardiovascular disease.

Research has shown significant gaps in knowledge on palliative services among neurology residents, resulting in low referral rates.

Despite a recent study concluding that oxygen therapy for cluster headache is not cost-prohibitive, many private payers and Medicare and Medicaid do not cover the effective therapy. Matthew Robbins, MD, Stewart Tepper, MD, and others weigh in on the controversial decision.

There is speculation that dystonia is the result of dysfunction occurring in either the cerebellum or basal ganglia or as a result of an abnormal interaction between the two.

Brief periods of oxygen deprivation to the brain have been shown to provide neuroprotective effects that reduce stroke infarct size and improve recovery times.

Future predictive models may need to include other migraine risk factors to enhance predictive accuracy.

The study group concluded that the current recommendation for CSF pressure reduction therapy to relieve headaches attributed to IIH should be removed from the International Classification of Headache Disorders 3b criteria.

In a disease where there have been few therapeutic developments since dopamine, exenatide offers a promising new channel of exploration.