Brandon May

Researchers sought to report the efficacy and safety data of adjunctive cenobamate in patients with uncontrolled focal seizures from a long-term open-label phase 3 study.

The effect of Vitamin D supplements in postmenopausal women are not well documented. A group of Turkish researchers conducted a study to assess the impact of vitamin D and exercise on balance, fall risk, and quality of life in this category of women.

Researchers sought to quantify and model the putative risk for cardiovascular disease related to the use of enzyme-inducing antiseizure medications in adult patients with epilepsy.

In a randomized placebo-controlled clinical trial, researchers measured whether methylphenidate, a catecholaminergic compound, compared with placebo decreases the severity of apathy in individuals with Alzheimer disease.

Researchers sought to determine the risk of hospitalization and death associated with pimavanserin use, a novel antipsychotic medication, in adult patients 65 years and older with Parkinson disease.

Using the Expanded Disability Status Scale and 25-foot walk times, researchers examined motor performance for upper and lower extremities in patients with multiple sclerosis at a registry enrollment.

Researchers sought to determine the status of neurologic assessment and magnetic resonance imaging compared with the Timed 25-Foot Walk test, a clinical tool that measures quantitative mobility and leg function performance, in patients with multiple sclerosis.

Researchers investigated the 5-year safety and efficacy of dimethyl fumarate under routine care in patients with multiple sclerosis in the ESTEEM trial.

Presenting at CMSC 2021, researchers evaluated the efficacy and safety of arbaclofen extended-release tablets in patients with multiple sclerosis-related spasticity.

Presenting at CMSC 2021, researchers compared adherence and persistence levels with peginterferon beta-1a and other injectable disease-modifying therapies in patients with multiple sclerosis.

Researchers investigated whether the incidence of psoriasis in patients with multiple sclerosis is associated with the use of certain disease-modifying therapies.

Researchers assessed the relationship between lifestyle physical activity and perceived physical and cognitive fatigue in patients with relapsing-remitting multiple sclerosis.

Researchers sought to determine whether cell-free DNA analysis of cerebrospinal fluid can be used to accurately diagnose leptomeningeal disease compared with cytologic analysis, the current diagnostic standard.

Researchers evaluated the safety and efficacy of sonothrombolysism, an ultrasound-enhanced thrombolysis, in patients with acute ischemic stroke with large vessel occlusion in randomized controlled clinical trials.

Researchers determined the effect of low-dose levetiracetam, an antiseizure drug, on cognitive function in patients with Alzheimer disease with epileptiform activity.

Researchers aimed to provide updated estimates of burden of overall stroke, ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage for 204 countries and territories in 21 GBD regions by age, sex, and country income level from the past 3 decades.

Using MRI, researchers assessed cortical, subcortical, and cerebellar grey matter atrophy in patients with frontotemporal lobar degeneration disorders, including motor neuron disease, with known genetic mutations.

Researchers sought to investigate clinical predictors of the effect of subthalamic nucleus-deep brain stimulation on impulsive and compulsive behaviors in patients with Parkinson disease.

Using a retrospective matched cohort design, researchers determined whether overall and cancer-specific survival following a colorectal cancer diagnosis is lower in patients with multiple sclerosis (MS) than without MS.

The investigators sought to determine the down-staging success rate and intention-to-treat outcomes according to uniform criteria in patients with hepatocellular carcinoma.

Researchers investigated the effects of a strength training program on function, activity, and participation in children and adolescents with cerebral palsy.

In a meta-analysis, researchers analyzed the effects of probiotics on disease progression, depression, general health, and anthropometric measures in patients with relapsing remitting multiple sclerosis.

This cross-sectional study assessed the frequency of peripapillary hyper-reflective ovoid masslike structures, a novel finding in retinal optical coherencetomography, in patients with early relapsing remitting MS and its link to disease duration in MS subtypes.

At MDS 2021, researchers shared results of a genetics investigative analysis on variations in the BSN gene in patients with multiple system atrophy.

At an abstract presented at MDS 2021, researchers described and analyzed eye movements in patients with an inborn errors of metabolism and their presence in early disease.

Researchers examined the effects of fluoxetine on functional outcomes in patients with acute stroke over a period of 12 months.

Researchers assessed the sex-specific association between self-reported sleep duration and mortality in an East Asian population.

This meta-analysis aimed to evaluate whether there’s evidence that supports the FDA-mandated warning for increased suicidality risk with antiseizure drug usage among people with epilepsy.

Population-based health record linkage data were used to examine risk of neurodegenerative diseases among former soccer players vs a matched general population control group.

Participants with both high and low tau levels who self-reported moderate to high levels of physical activity had a much slower rate of cognitive decline over time.