In a multicenter, retrospective, observational study, researchers examined real-world outcomes of patients with drug-resistant epilepsy treated with cenobamate as adjunctive treatment to other antiseizure medications.

Researchers investigated the clinical impact of the new ILAE epilepsy definition on diagnosis, treatment, and short-term outcome.

Investigators assessed epilepsy control after medial temporal lobectomy (with or without amygdalohippocampectomy) for management of drug-resistant temporal lobe epilepsy.

Researchers compared pTx and circularly polarized (CP) 7T MRI in adult candidates for epilepsy surgery who had negative or equivocal 3T MRI.

Radiprodil, a negative allosteric N-methyl-D-aspartate receptor subtype 2B modulator, has been seen to have an antiseizure effect in preclinical seizure and epilepsy models.

Researchers estimated the cumulative risk for epilepsy after neonatal seizures and identified subpopulations at increased risk in a register-based cohort study involving all children born in Denmark between 1997 and 2018.

Women with epilepsy may have offspring with decreased bone metabolism and lower birth weight, according to a study.

In a systematic review and meta-analysis, researchers looked at the prevalence of 20 psychiatric disorders in individuals with vs those without epilepsy.

Among simple congenital heart diseases (CHD), patent foramen ovale (PFO) is associated with a significantly higher risk for epilepsy.

Researchers sought to compare the outcomes of children aged 6 years of women with epilepsy vs healthy women, and assess the association of outcomes to antiseizure medication exposure in the 3rd trimester.

Researchers aimed to evaluate changes in total emergency department and inpatient visits and costs prior to and after referral to a functionals seizures clinic.

Researchers conducted a prospective study to explore the phenotypic spectrum of adults with CHD2 variants.

Researchers conducted the Japan Environment and Children’s Study to assess the relationship between maternal psychologic distress and pediatric epilepsy.

Epilepsy is associated with poor brain health, with a consistent deleterious effect seen on cognitive and motor function and mental health.

Socioeconomic deprivation increases the risk for sustaining a traumatic brain injury (TBI), and in some age groups.

Disability is a significant risk factor for lower quality of life (QOL) and increased caregiver burden among children with epilepsy and their caregivers.

Researchers aimed to determine the relationship between tetrahydrocannabinol positivity and epilepsy monitoring unit length of stay.

Risk for PSE was lower for patients treated with ARBs and higher for those receiving calcium channel blockers, beta-blockers.

Researchers explored whether common polygenic risk for epilepsy explains penetrance and phenotypic expression of rate pathogenic variants in familial epilepsies.

Findings based on smartphone home videos from children younger than 2 years.

Depressive symptoms, anxiety seen across patient groups referred to Austin Hospital First Seizure Clinic.

Higher risk for epilepsy also seen for sleep duration less than seven or more than eight hours per day, frequent insomnia, and daytime sleepiness.

Odds more than doubled when adjusting for sociodemographic factors.

No differences seen in six-year verbal abilities for children exposed, unexposed to antiseizure medications in utero.

Findings show up to 70 percent increased risk for offspring at ages 1, 2, and 3 years.

Researchers conducted a multicenter cohort study to determine antiseizure medication use patterns and their effects on outcomes in patients with acute symptomatic seizures.

People with a high number of antiseizure medications seem to be at risk for accelerated neuroaxonal loss.

Collinsella, Oscillospirales, and Ruminococcaceae have a greater impact on epilepsy with cognitive dysfunction.

Researchers conducted a prospective cohort study to determine the odds of new-onset cardiovascular events in older people with and without epilepsy.