The recommended dose for the treatment of MDD is 42mg once daily with or without food.

Researchers conducted a systematic literature review to assess the acute effects of fasting on cognitive performance.

Findings showed pegvaliase reduced mean blood Phe levels from baseline by 49.7% compared with 0.3% with diet only at week 72.

Researchers compared the use of aflibercept 8 mg and 2 mg in patients with various retinal vein occlusion subtypes.

Researchers examined the association of statins with attention, verbal fluency, and executive function in patients receiving doxorubicin for cancer.

Researchers mapped patterns of structural and functional retinal damage according to papilledema severity among patients with IIH.

Researchers evaluated visual acuity and optimized visual image quality in individuals with Down syndrome.

Researchers examined the baseline features of adults diagnosed with VS associated with subjective dizziness in a retrospective cohort study involving 109 patients who completed vestibular testing.

Researchers conducted a retrospective cohort study to identify predictors for pituitary adenomas among patients with multiple endocrine neoplasia type 1.

Researchers examined gabapentin dispensing from retail pharmacies in the United States from 2010 to 2024 in a cross-sectional study.

Researchers examined the impact of CI on vestibular symptoms in patients with MD in a retrospective chart review of patients who underwent CI between 2011 and 2024.

Researchers examined the association between depot medroxyprogesterone acetate exposure and meningioma incidence.

Researchers performed a meta-analysis evaluating the diagnostic accuracy and prognostic utility of intraoperative neuromonitoring in non-tumor thoracic spine surgeries.

Idebenone targets the mitochondrial dysfunction of retinal ganglion cells to prevent vision loss.

Researchers conducted a double-blind, randomized trial involving 99 patients selected for shunt surgery on the basis of gait-velocity improvement with CSF drainage.

Researchers evaluated the prevalence, impact, and risk factors of neurologic manifestations in children with COVID-19 or multisystem inflammatory syndrome.

Researchers evaluated the relationship between depression and regional brain volumes in older adults from the National Alzheimer’s Coordinating Center database.

Researchers evaluated whether prepandemic memory function was associated with COVID-19 hospitalization and mortality among adults aged 50 years and older.

According to Saol, the CRL included specific requirements that “would take several years and require significant financial resources.”

Investigators examined the association between chronic tinnitus and cognitive function in adults aged 60 years and older and assessed whether the risk for cognitive impairment was increased in association with severity and duration of tinnitus in a cross-sectional study conducted among older adults.

Researchers used genome-wide association study genetic data from individuals of European ancestry to examine the correlation between GERD, Barrett esophagus, and ear disorders.

Researchers examined the association between LNCS consumption and cognitive decline in a longitudinal observational study using data from civil servants aged 35 years and older at baseline who were enrolled in the Brazilian Longitudinal Study of Adult Health.

Researchers developed a method to biopsy a small volume of PFC tissue during DBS lead placement procedures.

Researchers compared intraoperative and postoperative outcomes for patients with public vs private insurance undergoing meningioma resection.

Researchers conducted the SWAN HDL ancillary study to assess the relationship between HDL-C metrics and midlife cognition among women.

Researchers compared patterns of white-matter hyperintensities between patients with systemic sclerosis vs healthy controls.

Investigators examined the linkages between 2 forms of helping behaviors and late-life cognitive function, focusing on changes in these behaviors over time.

The extension was needed to review newly submitted long-term clinical data for all patients in the pivotal study following an FDA information request.

Investigators examined the incidence of eye disorders, diabetic retinopathy, and nonarteritic anterior ischemic optic neuropathy in adults treated with semaglutide in a systematic review and meta-analysis.

Researchers utilized longitudinal neuroimaging data to examine the effect of the COVID-19 pandemic on brain age.