The US Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced Parkinson disease.
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Onapgo is a wearable subcutaneous infusion device that delivers apomorphine.
Antipsychotics at doses >75 mg/day are associated with an increased risk for tardive dyskinesia (TD), according to a study.
Hearing impairment is a risk factor for incident Parkinson disease (PD), according to a study published online.
Females with Tourette syndrome (TS) are less likely than males to be formally diagnosed, with symptom onset and diagnosis occurring at a later age for females.
An expert panel of physicians, nurses, pharmacists, and therapists issued new recommendations to improve hospital care for patients with Parkinson disease.
Researchers sought to assess the association between hearing loss and the risk for Parkinson disease among US veterans.
Black adults are diagnosed later than White adults.
Overground gait training with wearable robot improves gross motor function and gait pattern.
Researchers conducted a population-based case-control study to evaluate if air pollution is linked to an increased risk for Parkinson disease.
Increase in PD risk seen in association with exposure to two or more courses of antifungals one to five years prior.
Change in Modified Fatigue Impact Scale scores did not differ between the groups.
Findings seen after adjusting for lifestyle factors and comorbidities.
Researchers conducted a retrospective cohort study to determine whether upper gastrointestinal mucosal damage is linked to increased Parkinson disease risk.
In an analysis of 2 studies, researchers assessed long-term dementia risk in patients with Parkinson disease.
In the TEMPO-1 trial, participants with early PD were randomly assigned to receive tavapadon 5mg or 15mg once daily or placebo.
PTC518 is an orally taken small molecule discovered from RNA splicing technology.
Development of paramagnetic rim lesions tied to more rapid disability progression.
Researchers conducted a prospective cohort study to explore the relationship between napping duration and frequency and Parkinson disease incidence.
Single injection of botulinum toxin A into calf muscles may result in a larger reduction in pain intensity at 12 weeks.
In a cross-sectional study, researchers assessed the risk for parkinsonism in athletes with CTE and the association of repeated head injuries and neuropathologic substrates on this risk.
In a retrospective cohort study, researchers investigated the incidence of Parkinson disease in adults with anxiety aged 50 and older and the clinical features tied to a later PD diagnosis in this patient population.
In a randomized clinical trial, researchers evaluated the safety and efficacy of acupuncture as therapy for patients with Parkinson disease who have poor sleep quality.
At six months, no significant changes seen in Movement Disorder Society Unified Parkinson’s Disease Rating Scale scores versus placebo,
Certain clinical features may identify those who may be in prodromal phase of Parkinson disease.
Using large-scale claim data from the LIFE study, investigators aimed to elucidate the association between statin use and Parkinson disease among Japanese adults.
Benefits persist four weeks after treatment.
Models including disease exposure indexes predict gray matter atrophy accumulation.
Approval allows for use in nonambulatory individuals ≥4 years with a confirmed gene mutation.
Change in digital measures over 12 months generally larger than corresponding change in individual items of the Movement Disorder Society scale.