Animal models suggest that naloxone may be a potential microglia inhibitor, which can also impact the sleep-pain relationship.
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Nearly two-thirds of trials had one or more authors with financial conflicts of interest.
The researchers recommend that older adults be vaccinated to prevent long-term complications of shingles.
Women with fibromyalgia may benefit from hyperbaric oxygen therapy (HBOT).
The effects were also apparent in patients exposed to secondhand smoke.
Following a vegan diet helped lower levels of pain and promote weight loss in patients with diabetic neuropathy.
Patients with fibromyalgia had poorer health status, function, sleep, and faced higher costs.
TEAS treatment for 10 days cut rescue opioid requirement.
In addition to contributing significantly to cancer pain, researchers believe cancer progression depends largely on nerve activity.
About 15 trials of medical cannibinoids have been conducted worldwide, indicating effectiveness in reducing pain from cancer, diabetes, fibromyalgia, and neuropathy
While their are many benefits, researchers warn of the potential to create illegal drugs with the new pathway.
There was actually no difference in pain between the two groups.
High doses of the SNRI venlafaxine may alleviate depression and chronic pain in older patients.
Medical marijuana users still use more alcohol and drugs than the general population, but adding prescription pain meds does not increase this risk.
Imaging studies show that the brains of chronic pain patients differ from healthy control subjects.
The therapy is approved for children 12 years and older with migraine with or without aura.
Since celiac is a possibly treatable condition, the authors suggest screening neuropathy patients for celiac disease.
The authors do not recommend additional randomized controlled trials (RCTs) comparing a SSRI or SNRI vs. non-pharmacological drug.
Those already addicted may be seeking illicit narcotics as a substitute, contributing to the surge in heroin use.
Aerobic exercise intervention doesn’t seem to change pain severity, but seemed to lessen pain interference in daily activities.
Research into the “wasabi receptor” could lead to new insights into pain.
Participants had lower levels of anxiety and depression, better mental quality of life, and had higher pain acceptance.
Despite the data on incidence, the report does not identify causality.
Many are unsure that the benefits of opioid use outweigh the burden of addiction.
Two studies show clinically significant improvement of ‘minimum change in pain’ measure.
The guidance includes studies that the FDA believes should be conducted in order to demonstrate that a opioid formula has abuse-deterrent properties.
HHS has announced an initiative to reduce prescription opioid and heroin related overdose, death, and dependence.
A low dose of dermal filler cross-linked hyaluronic acid was injected into patients’ pain points.
Pfizer and Eli Lilly and Company plan to resume the Phase 3 trial of tanezumab after the FDA lifted the clinical hold.
The evolution of monoclonal antibody treatment is an important development for the treatment and management of migraines.
