In a prospective cohort study, researchers assessed the incidence of and factors associated with PIRA and relapse-associated worsening in pediatric-onset MS compared with typical adult-onset MS and late-onset MS.

In a retrospective observational study, researchers determined the frequency and risk factors for fingolimod rebound.

In a systematic review and meta-analysis, researchers assessed the efficacy of various electrical stimulation therapy treatments in alleviating pain among patients with MS.

Researchers sought to investigate the rates and reasons for dimethyl fumarate discontinuation among patients with MS on a national level and differences between sites in Denmark.

In a systematic review and meta-analysis, researchers assessed randomized controlled trials on the effectiveness of remote forms of exercise and physiotherapy on the depressive symptoms of patients with MS.

These findings are independent of clinical multiple sclerosis relapse.

In a systematic review, researchers assessed associations between cumulative PPI use and dementia at different ages in a nationwide Danish cohort.

Pretreatment vitamin D insufficiency linked to increased incidence of grade ≥3 chemotherapy-induced peripheral neuropathy.

Findings show doubling of odds of physical multimorbidity with eating disorder.

Investigators evaluated the impact of secondhand cannabis exposure on psychotic-like experiences in children using the Adolescent Brain Cognitive Development® study data.

Investigators utilized Generation R study data to examine the association between common prenatal infections and changes in adolescent brain morphology.

Investigators conducted a prospective birth cohort study using electronic health records from a HMO to examine the association between adult ADHD and dementia.

In a retrospective cohort study, researchers assessed the relationship between thyrotoxicosis and cognitive disorder risk.

Researchers hypothesized that microvascular function in heart failure is closely related to both cardiac and cognitive function.

In a meta-analysis, researchers assessed the link between short-term exposure to air pollutants and stroke incidence and mortality.

Children with polygenic risk score for insomnia have more insomnia-related sleep problems between ages 1.5 and 15 years.

Composite measure of perceived stress associated with atherosclerotic and global cardiovascular disease.

Researchers conducted a study to compare methylphenidate and atomoxetine in their efficacy treating behavioral, emotional, and motor symptoms in children with ADHD.

A study was conducted to determine optimal apixaban therapy for atrial fibrillation in patients with chronic kidney disease.

Investigators evaluated evidence regarding the impact of atopic dermatitis from the patient’s perspective.

In a meta-analysis, researchers assessed the influence of antidiabetic medications on the association between diabetes and dementia risk.

Researchers sought to compare the rates of COVID-19-related hospitalization and mortality among patients with MS and those without MS.

In a nationwide French study, researchers assessed whether vaccination was associated with the risk for hospitalization due to MS flare-ups.

Researchers sought to assess the association between disability, fatigue, and accelerometer-measured physical activity among patients with RRMS.

In an observational study, researchers investigated the efficacy of rituximab/ocrelizumab suspension preconception vs natalizumab during pregnancy in reactivating multiple sclerosis.

In a double-blind, placebo, randomized clinical trial, researchers assessed the efficacy of teriflunomide in delaying multiple sclerosis progression in patients with radiologically isolated syndrome.

Disease-modifying therapies have minimal transfer into breast milk and is safe and well-tolerated by both the mother and the baby, a study found.

Males with diabetes seem to be more prone to have progressive demyelinating disorders, but more research is needed, a study found.

In a systematic review and meta-analysis, researchers assessed whether noninvasive brain stimulation can effectively reduce the most common symptoms in patients with multiple sclerosis.

The Food and Drug Administration has approved Tyruko (natalizumab-sztn), a biosimilar to Tysabri (natalizumab).