Nearly half of the patients in the trial survived more than 5 years after they were given the vaccine-chemotherapy treatment.
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Despite previous reports, researchers have found no signs of a link between cytomegalovirus and brain tumors including glioblastoma.
Molecular changes occur to cancer cells when they spread to the brain.
Radiomic-based superpc signature stratifies patients into low- or high-risk groups for PFS, OS.
Despite it being a standard of care, more or more pediatric patients are deferring PORT.
Intracranial disease control at 3 months was better with combination therapy; however it did not appear to impact overall survival.
GTR increases survival by about 61% at 1 year compared to STR.
Researchers achieved a 3-year event-free survival rate of 73.2% for tandem transplant patients.
The role of antiangiogenic agents continues to evolve in the treatment of CNS cancers.
Researchers were able to identify 8 genes that showed the highest association to outcomes.
Multiple modalities were found to be superior to single modality therapies in elderly patients with glioblastoma.
Interestingly, the risk of death and tumor progression was increased in low-grade gliomas.
Those who received both treatments lived longer than those who received radiation alone.
Over 10 000 brain and CNS tumors are diagnosed in adolescent and young adults each year.
Proton radiotherapy showed acceptable toxicity and similar survival compared to conventional radiotherapy.
The association may be mediated by mechanisms dependent on matrix metalloproteinases.
Two years post-enrollment, 43% of patients in the combination therapy group were alive.
The adaptive trial design will allow GBM patients to benefit from precision medicine.
Researchers found that brain tumor mutations could be detected from ctDNA in cerebrospinal fluid.
The device may now be used to treat newly-diagnosed patients in combination with temozolomide.
A reduction primarily in grey matter and expansion of the brain’s ventricles was observed.
Researchers found an association between obesity and meningioma risk, but not for glioma.
The combination therapy specifically targets glioblastoma cells.
Two studies classified gliomas into distinct subtypes by analyzing their genomes.
Treatment does not cause significant increase in incidence of intracranial hemorrhage
Survival rates were similar for both methods, but targeted radiation helped preserve cognition.
Watson can analyze and interpret genetic data in minutes — a process that normally takes physicians weeks to complete.
The combination of two histone inhibitors seemed to slow DIPG cell growth even further.
Researchers also found mechanisms of cell survival in ischemic regions of brain tumor.
On average, 65% of cancer patients survived after a period of 5 years, but survival was lower among black people.
